With an aging population and a higher prevalence of cancer among the general population, endodontists have to be familiar with the special considerations for successful managemetn and treatment of such patients. In this video interview, Dr. Ian Grayson, Post Doctoral Fellow at Harvard School of Dental Medicine Post-Doctoral Endodontics program reviews and discusses important considerations for managment of patients who have cancer and are at various stages of treatment and its relevance on the endodontic care.